An Introduction to Neuroendocrinology by Richard Brown

By Richard Brown

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P. Plotnikoff, R. E. Faith, A. J. Murgo and R. A. ) Enkephalins and Endorphins: Stress and the Immune System, pp. 119-127. New York: Plenum Press. Smythies, J. R. (1976). Perspectives in psychoneuroendocrinology. Psychoneuroendocrinology, 1, 317-319. Snyder, S. (1985). The molecular basis of communication between cells. Scientific American, 253 (4), 114-123. Sporn, M. B. and Roberts, A. B. (1988). Peptide growth factors are multifunctional. Nature, 332, 217-219. Tausk, M. (1975). Pharmacology of Hormones.

Many hormones of the GI tract do not meet the criterion of 'true' hormones because they are not secreted from specific endocrine glands and their action at target cells has not been specified (Turner and Bagnara, 1976; Johnson, 1977). The release of many GI hormones is controlled by nerves of the autonomic nervous system, so such hormones form an integral part of the neuroendocrine system. The three primary gastrointestinal hormones, secretin, gastrin and cholecystokinin, are produced in endocrine cells scattered throughout the walls of the alimentary tract, rather than in specialized endocrine glands.

Prolactin is produced in lactotroph (or mammotroph) cells in the adenohypophysis. Prolactin has also been called luteotropin, luteotropic hormone and lactogenic hormone, but these terms are rarely used now.

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