By Gunter Wolf
Diabetes and the Kidney provides endocrinologists and nephrologists of all degrees with professional clinical diagnosis and administration assistance for this super common diabetic complication.
Practical and accessible, chapters contain text beneficial properties resembling case histories, capability pitfall packing containers, key issues, administration algorithms, and worthwhile weblinks to fully have interaction the reader and supply professional tips to aid clinicians top deal with their patients. moreover, all relevant international society directions and proposals are absolutely included.
After an preliminary research of the epidemiology and pathogenesis of kidney issues in diabetes, it quick strikes directly to the next middle sections:
• Special occasions, probability components and issues - reading diabetic nephropathy when it comes to one another diabetic hardship, ie cardiovascular disease
• Prevention and treatment - concentrating on the freshest information about prevention, analysis, therapy, and administration of kidney affliction in diabetes.
Expertly edited, and with contributions from an skilled foreign staff, Diabetes and Kidney ailment could be the ideal device to refer to while handling diabetic sufferers with linked kidney problems.
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Additional resources for Diabetes and Kidney Disease
Klein R, Klein BE, Moss SE, et al. The Wisconsin epidemiologic study of diabetic retinopathy. IV. Diabetic macular edema. Ophthalmology 1984;91: 1464–74. 4. Seaquist ER, Goetz FC, Rich S, Barbosa J. Familial clustering of diabetic kidney disease. Evidence for genetic susceptibility to diabetic nephropathy. N Engl J Med 1989;320:1161–5. 5. Quinn M, Angelico MC, Warram JH, Krolewski AS. Familial factors determine the development of diabetic nephropathy in patients with IDDM. Diabetologia 1996;39:940–5.
N Engl J Med 2008;358: 2560–72. Patel A, MacMahon S, Chalmers J, Neal B, Woodward M, Billot L, et al. Effects of a ﬁxed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial. Lancet 2007;370:829–40. UK Prospective Diabetes Study Group. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. BMJ 1998;317:703–13. Remuzzi G, Benigni A, Remuzzi A.
In a recent study with 576 con32 secutive biopsies, the diagnoses of those without non-diabetic kidney disease were mostly immune complex glomerulonephritis and secondary focal glomerulosclerosis . , associations with undiagnosed glomerulopathy). 3. In patients with diabetes who have reduced eGFR but normal albuminuria, underlying hypertensive nephropathy (so-called benign nephrosclerosis) is a likely diagnosis given the high prevalence of hypertension in diabetes patients. This is supported by data from diabetic patients, where a substantial proportion develops decreased eGFR without concurrent or prior elevated albuminuria [31, 32].