Embryo and Fetal Pathology: Color Atlas with Ultrasound by Enid Gilbert-Barness

By Enid Gilbert-Barness

Exhaustively illustrated in colour with over one thousand pictures, figures, histopathology slides, and sonographs, this uniquely authoritative atlas offers the clinician with a visible consultant to diagnosing congenital anomalies in each organ approach within the human fetus. It covers the total diversity of embryo and fetal pathology, from aspect of demise, post-mortem and ultrasound, via particular syndromes, intrauterine difficulties, organ and system faults to a number of births and conjoined twins. Gross pathologic findings are correlated with sonographic positive aspects to substantiate visually the diagnoses for all organ structures.

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21. Mechanisms of erythroblastosis fetalis. 22. Erythroblastosis fetalis. (A) Hydropic infant with anemia due to Rh blood group incompatibility. The mother was Rh negative and had not received Rhogam at a previous delivery. (B) Microscopic section of the placenta showing persistence of the cytotrophoblasts and nucleated red blood cells in the villus capillaries. Metabolic Disorders (see Chapter 24) Metabolic disorders have been related to unexpected death in newborns. In these disorders, there is usually a normal period immediately after birth followed by hypoglycemia, respiratory difficulty, vomiting, and acidosis.

Cord prolapse and compression cannot be confirmed pathologically. 6). 2 Causes of fetal death Cause of death Percentage of deaths Hypertensive disease (pre-eclampsia and pregnancy-induced hypertension) 25 Maternal medical complications Maternal diabetes Connective tissue disorders 10 Erythroblastosis fetalis 5 Umbilical vessel thrombosis and cord and placental complications Abruptio placental Placenta infarction Maternal smoking with placental fibrin deposition Maternal floor infarction 30 Congenital malformation 10 Intrauterine infection 15 Unexplained 5 Source: Pitkin RM: Fetal death: Diagnosis and management.

CR measurement of embryos. (A) Early embryo (32 days developmental age). (B) Embryo at about 7 weeks developmental age. (C) Illustrations demonstrating development of the hand and foot. of a blighted ovum is an intact but empty sac without a trace of an embryo. Incomplete specimens consist of an opened or ruptured chorionic sac without an identifiable embryo. Curetted specimens are most often incomplete. When an embryo is identified, it should be measured and assessed for all developmental features, such as limb development, eyes, branchial arches, etc.

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