Williams Textbook of Endocrinology (12th Edition) by Shlomo Melmed, Kenneth S. Polonsky, P. Reed Larsen, Henry M.

By Shlomo Melmed, Kenneth S. Polonsky, P. Reed Larsen, Henry M. Kronenberg

The most recent variation of Williams Textbook of Endocrinology edited by way of Drs. Shlomo Melmed, Kenneth S. Polonsky, P. Reed Larsen, and Henry M. Kronenberg, is helping you diagnose and deal with your sufferers successfully with up-to-the minute, useful knowledge on all endocrine approach issues. finished but obtainable, this generally revised twelfth version updates you on diabetes, metabolic syndrome, weight problems, thyroid ailment, testicular issues, and lots more and plenty extra so that you grants your sufferers with the main winning remedies. locate medical perception and scientific info interwoven in each bankruptcy, reflecting advances in either components of this always altering self-discipline, and offered in a very available layout. You'll additionally entry necessary contributions from a dynamic record of specialist authors and approximately 2.000 full-color pictures that will help you with each prognosis. in addition to handy on-line entry at www.expertconsult.com, this identify has every little thing you want to deal with any and all of the scientific endocrinopathies you'll encounter.

* depend upon the only reference that integrates speedily evolving easy and scientific technological know-how in a cohesive, elementary structure, definitively addresses each subject within the box, and has remained a regular for greater than part a century.
* replace your information and abilities to diagnose and deal with your sufferers such a lot successfully with exhaustively revised content material on diabetes, metabolic disorder, thyroid melanoma, fertility difficulties, testicular difficulties, weight matters, and masses more.

* follow trustworthy information on endocrine stipulations of becoming curiosity like hypothyroidism and testicular issues, with devoted new chapters that expound at the most up-to-date study findings.

* triumph over any scientific problem with accomplished and easy-to-use insurance of every little thing from hormone job, diagnostic ideas, imaging modalities, and molecular genetics, to overall care of the patient.

* follow the most recent practices with information from specialist authors who give a contribution clean views on each topic.

* seek the entire contents on-line, obtain all of the photos, and entry hyperlinked references to PubMed at www.expertconsult.com.

Your imperative resource for authoritative endocrinology guidance.

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Sample text

It may be useful in the emergency treatment of endogenous Cushing’s syndrome or severe glucocorticoid excess. • Recognition of the downregulation of luteinizing hormone and FSH that occurs after administration of exogenous gonadotropin-releasing hormone (GnRH) has led to the development of GnRH analogues that inhibit gonadotropin release. THE ENDOCRINOLOGIST AS ONCOLOGIST Although it is easy to frighten patients, it takes time, patience, and sensitivity to reassure them. ” But for nodules that are obviously not serious malignancies, it would be far better and equally honest to tell the patient, “You have a thyroid nodule.

An elevated alkaline phosphatase concentration is common in patients with untreated Graves’ disease. With treatment, the alkaline phosphatase level usu­ ally rises further (as bone heals) and may remain above normal for up to 1 year after the patient is euthyroid. • A white blood cell count with 1% or 2% eosinophils almost always excludes overt Cushing’s syndrome. 7 This is not a contraindication to anti-thyroid drug therapy. • Hyponatremia without hyperkalemia may be a consequence of glucocorticoid deficiency from central causes.

Always consider the value of the diagnostic information that a biopsy could provide, particularly with ever-smaller thyroid nodules. For example, think about whether there really is an advantage to diagnosing a 5-mm papillary thyroid carcinoma. Likewise, common sense and judgment should lead to treating many nodules more conservatively in the aged. Whereas larger nodules in older patients may be aggressive malignancies, it is reasonable to tell octogenarians who present with five or six thyroid nodules of modest size that even if the risk of malignancy is about 10%, the risk of death from such malignancies is quite remote.

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