By Jerome Strauss, Robert Barbieri
For greater than 25 years, Reproductive Endocrinology has stood because the greatest reference at the services and problems of human replica. Now a brand new version returns with all of its conventional strengths-coupled with the very most recent details! up to date all through, the fifth version positive factors the paintings of latest editors Jerry Strauss, MD, and Robert Barbieri, MD-leaders within the box of reproductive endocrinology. jointly, with a staff of the world over famous specialists, they discover what readers want to know to effectively diagnose and deal with nearly each reproductive endocrine disorder.• contains thirteen completely new chapters that hide today's most well liked topics.
• gains 24 chapters with new subject matters or new authors that discover themes shaping today's practice.
• Covers the entire spectrum of reproductive pathophysiology and problems, from being pregnant and beginning to reproductive aging
• deals a brand new part on reproductive applied sciences that emphasizes the developments in reproductive know-how, together with in vitro fertilization * intracytoplasmic sperm injection * genetic innovations which are utilized to gametes and embryos * new methods to utilizing recombinant gonadotropins to urge ovulation * and endocrinology of getting older in women and males.
• Discusses scorching subject matters similar to the remedy of andrology, gamete biology suitable to assisted reproductive know-how, the endocrinology of getting older, and hormones and cancer.
• includes a reorganized and streamlined layout for better ease of use
Read Online or Download Yen and Jaffe's Reproductive Endocrinology: Physiology, Pathophysiology, and Clinical Management (6th Edition) PDF
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Extra resources for Yen and Jaffe's Reproductive Endocrinology: Physiology, Pathophysiology, and Clinical Management (6th Edition)
In humans, the expression of somatostatin and VIP is sexually differentiated in the bed nucleus of the stria terminalis (Fig. , sexual behavior, aggression, exploration); however, in many cases, the physiologic significance of sex differences in the pattern and degree of neurotransmitter expression is unknown. The mechanisms through which sex steroids permanently alter the expression of neurotransmitter systems are believed to involve regulation of apoptosis (programmed cell death), neuronal migration, neurite outgrowth, synaptogenesis, and astrocyte morphology.
Despite the absence of any striking sequence homology, the two subunits in both heterodimers have similar folds, characterized by three major loops, and each subunit contains a cystine knot motif, consisting of three disulfides located in the core of each subunit. The α and β subunits contain, in addition to the three disulfides in the cystine knot, two and three disulfides, respectively. In both hCG and hFSH, the two subunits are associated in a head-to-tail arrangement. Although there are no structures available for LH and TSH, the similarities of the hCG and FSH structures engender confidence that the overall conformations of LH and TSH will be closely related to the known structures.
Oxford, Elsevier, 2006, pp 2553-2625. Page RB. Anatomy of the hypothalamo-hypophysial complex. In Neill J (ed). Knobil and Neill’s Physiology of Reproduction, vol 2. Oxford, Elsevier, 2006, pp 1309-1413. Popa S, Clifton D, Steiner R. The role of kisspeptins and GPR54 in the neuroendocrine regulation of reproduction. Annu Rev Physiol 70:213238, 2008. Simerly R. Wired for reproduction: Organization and development of sexually dimorphic circuits in the mammalian forebrain. Annu Rev Neurosci 25:507-536, 2002.